Published in bioRxiv, currently in 2nd review in Nature Micro, 2025
Studing ionic control of porin permeability in bacteria at the single-cell level.
Recommended citation: Muniz, Santiago Cano., et al. (2022). "Ionic control of porin permeability in bacteria." bioRxiv
Published in bioRxiv, currently in review, 2024
Dissecting the lytic phage lifecycle by imaging phage infections at the single virion and cell level in the mother machine.
Recommended citation: Wedd, Charlie., et al. (2024). "Single-cell imaging of the lytic phage life cycle in bacteria." bioRxiv (in review)
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Published in npj Imaging, 2024
Analysing optical artefacts affecting quantification of single-cell parameters using virtual microscopy and bioimage analysis of targetted experiments.
Recommended citation: Hardo, Georgeos., et al. (2024). "Quantitative microbiology with widefield microscopy: navigating optical artefacts for accurate interpretations." npj Imaging
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Published in BMC Biology, 2022
A tool to generate synthetic training data of bacteria under the microscope to train highly accurate and precise segmentation and tracking models.
Recommended citation: Hardo, Georgeos., et al. (2022). "Synthetic Micrographs of Bacteria (SyMBac) allows accurate segmentation of bacterial cells using deep neural networks." BMC Biology. 20, 263.
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Published in Essays in Biochemistry, 2021
Here we look at the issues surrounding measurement of single-cell gene expression in bacteria growing in microfluidic devices such as the mother machine.
Recommended citation: Hardo, Georgeos., Bakshi, Somenath. (2021). "Challenges of analysing stochastic gene expression in bacteria using single-cell time-lapse experiments." Essays in Biochemistry. 65(1).
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